Working together to
promote the advance
of all aspects of
cancer research.

Senior Bioscientist - Drug Discovery Unit

  • Salary in the range of £24,776 to £41,536 (dependent upon experience)
  • Job Ref: MI/18/98
  • Duration: fixed term until  31 March 2020 (in the first instance)

About the role:

They are currently looking for a Senior Bioscientist to join the Drug Discovery Unit to establish and build our protein production capability. The senior protein production scientist will support a wide range of drug discovery and development efforts which includes screening and lead discovery. As a member of a multi-disciplinary team, you will be responsible for construct design, expression analysis and development and application of purification protocols in order to produce high quality protein reagents for screening and biophysics. This post would suit a highly motivated, conscientious and well organised individual, who is looking for the opportunity to support the day-to-day running of a busy drug discovery laboratory.

About you:

You should have a degree in a Biological discipline (or equivalent relevant experience) and have excellent molecular biology skills for construct design and an applied knowledge of optimising protein expression conditions across diverse host systems (such as bacterial, insect and mammalian). You will be experienced with a range of protein purification techniques and have experience of AKTA systems or similar. Additionally you will be familiar with methodologies for the Quality Control and characterization of recombinant proteins. You will be a hardworking, detail-orientated person who is able to function effectively in a fast-paced and multi-disciplinary team environment.


Why choose Cancer Research UK Manchester Institute?

The Cancer Research UK Manchester Institute (, an Institute of The University of Manchester (, is a world-leading centre for excellence in cancer research.  The Institute is core funded by Cancer Research UK (, the largest independent cancer research organisation in the world.  They are currently situated at the internationally-renowned life sciences campus at Alderley Park in Cheshire England, 15 miles from Manchester, a vibrant and dynamic city surrounded by beautiful countryside.

They are partnered with The Christie NHS Foundation Trust (adjacent to the CRUK MI Paterson Building) in South Manchester (, one of the largest cancer treatment centres in Europe.  These factors combine to provide an exceptional environment in which to pursue basic, translational and clinical research programmes.

The Drug Discovery Unit employs state-of-the-art facilities directed toward the discovery of novel, clinically relevant treatments for a variety of different cancer types. Details of the Unit itself can be found at (

How to apply?

To apply for this position please visit our website:

For any informal enquiries about this post, please contact the recruiting line manager Dr Graeme Thomson, Head of Biochemistry via email:

Start Date

12th December 2018

Closing Date

27th January 2019