Working together to
promote the advance
of all aspects of
cancer research.

Lead Biologist

·         Salary in the range of £31,334 - £51,113 (dependent upon experience)

·         Job Ref: MI/18/103

·         Duration: Fixed term until 31 March 2020 (in the first instance)


About the role:

They are currently looking for a Lead Biologist within the Drug Discovery Unit.


The successful candidate will devise, implement and deliver the biology strategy for lead optimisation projects progressing towards clinical candidate nomination.  As the leader of a small multidisciplinary biology team you will have an excellent understanding of the drug discovery process to ensure the biology team delivers data which enables compound profiling, mechanistic understanding, disease positioning and clinical biomarker identification.  You should also have significant cell biology experience and make a meaningful contribution to the practical delivery of projects.


This post will suit a highly motivated drug discovery expert who enjoys leading and working in multidisciplinary teams.


About you:

You will have a BSc in Biological Sciences or related subject and a successful track record in drug discovery obtained in an academic, biotech or pharma environment.  You should have experience of leading a discipline within a project, working across boundaries to achieve project aims and managing research collaborations.  You should also have exposure to a wide range of biochemical and cellular techniques relevant to drug discovery and extensive cancer research experience.  A PhD in Biological Sciences is desirable but not essential.


Extensive knowledge of one or more areas of cancer biology, expertise of techniques to identify and measure pharmacodynamics biomarkers and experience of positioning agents in the clinic versus patient populations is desirable but not essential.


Why choose Cancer Research UK Manchester Institute?

The Cancer Research UK Manchester Institute (, an Institute of The University of Manchester (, is a world-leading centre for excellence in cancer research.  The Institute is core funded by Cancer Research UK (, the largest independent cancer research organisation in the world. We are currently situated at the internationally-renowned life sciences campus at Alderley Park in Cheshire England, 15 miles from Manchester, a vibrant and dynamic city surrounded by beautiful countryside.


They are partnered with The Christie NHS Foundation Trust (adjacent to the CRUK MI Paterson Building) in South Manchester (, one of the largest cancer treatment centres in Europe.  These factors combine to provide an exceptional environment in which to pursue basic, translational and clinical research programmes.


The Drug Discovery Unit was established in 2009 and has a strong record of candidate drug delivery with successful project collaborations with AstraZeneca, GSK and biotech partners. 

The Unit has state-of-the-art facilities directed toward the discovery of novel, clinically relevant treatments for a variety of different cancer types


How to apply?

To apply for this position please visit their website:   


For any informal enquiries about this post, please contact Dr Graeme Walker, email:


The deadline for receipt of applications is: 17 February 2019.



Start Date

17th January 2019

Closing Date

17th February 2019