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BACR – Breast Cancer Conference, Gateshead 25th –27th November 2024 – Programme
Monday 25th
12:00 – 13:00 Registration (coffee)
Introduction
13:00 – 13:15 Simon Vincent – Breast Cancer Now (Welcome)
13:15 – 13:45 Patient advocate speakers - Patricia Fairbrother and Hillary Stobart
Advances in treatments for breast cancer
13:45 – 14:30 Thomas Helleday – PARP inhibitors from bench to bedside
14:30 – 15:00 Jean Abraham – emerging treatments for breast cancer
15:00 – 15:30 Karen Blyth – In vivo models for studying breast cancer
15:30 – 16:00 Break
Bridging the gaps
16:00 – 16:30 Anna Campbell – Critical gaps and translation priorities concerning lifestyle for prevention and treatment of breast cancer
16:30 – 17:00 Val Speirs – Male breast cancer
17:00 – 17:30 Flash poster presentation (90 seconds each)
17:30 – 19:00 Poster presentations and reception
19:30 - Speakers meal
Tuesday 26th
Mechanisms of tumourigenesis and metastasis
09:00 – 09:45 Seth Coffelt – Immune cells as regulators of breast cancer development
09:45 – 10:30 Damir Vareslija – Epigenetic control of breast cancer brain metastasis
10:30 – 10:45 Heba Sailem - Decoding spatial mTOR signalling reveals a differential role for mTOR in the tumour microenvironment
10:45 – 11:00 Ashia Wheeler Crawford - The Role of bromodomain and extra terminal (BET) proteins in angiogenesis in triple negative breast cancer.
10:30 – 11:00 Break
Mechanisms of chemo resistance
11:00 – 11:30 Kirsty Sawicka – Mechanisms of chemo resistance
11:30 – 12:00 Luca Magnani – endocrine resistance and dormancy
12:00 – 12:30 Flash poster presentations (90 seconds each)
12:30 – 14:00 Lunch and poster presentations
Research resources
14:00 – 14:30 Louise Jones – Tissue banking
14:30 – 15:00 Claude Chelala – Bioinformatics analysis of large data sets
15:00 – 15:15 Nina Moderau - Deconvolution of heterogenous 3D breast cancer spheroid dynamics over 8 days at single-cell resolution for cancer drug screening utilising Oblique plane microscopy (OPM)
15:15 – 15:30 Rebecca Allsopp - Concurrent mutational assessment of circulating tumour cells and ctDNA to guide therapy in metastatic breast cancer
15:30 – 16:00 Break
Model systems for studying breast cancer
16:00 – 16:30 Robert Clarke – 3D models for studying breast cancer metastasis
16:30 – 16:45 Riba Thomas - Human stem cell models of de novo tumorigenesis for the study of cancer development
Novel treatment strategies and resistance mechanisms
16:45 – 17:00 Ioanna Mavrommatis - Deconvoluting the intra-tumour heterogeneity and subclonal evolution of CDK4/6 inhibitor resistance in ER+ breast cancer
17:00 – 17:15 Jiabao Zhou - Combining Anakinra with Paclitaxel and Zoledronic acid reduces metastatic outgrowth of triple-negative breast cancer cells in mouse bone and soft tissues
17:15 – 17: 30 Charlene Kay - ER+/HER2+ Breast Cancer – Can Some Patients be Managed on Endocrine Therapy Alone?
Career development session
17:30 – 18:30
Sankari Nagarajan – University of Manchester
Carolyn Staton – University of Sheffield
From research Scientist to academic teacher alternative career options
Andrew Reynolds - AstraZeneca, Cambridge, UK
A journey from academia to industry
19:00 - Conference dinner
Wednesday 27th
Molecular regulation of breast cancer
09:00 – 09:45 Mohamed Bentires-Alj: Tumour heterogeneity and metastasis resistance.
09:45 – 10:15 Jo Morris – DNA replication and DNA damage repair in breast cancer
and response to treatment
10:15 – 10:30 Siang Boon Koh - A functional crosstalk between a RAS regulator and mitochondrial resilience in chemo refractory triple-negative breast cancer
10:30 – 10:45 Bruno Simoes - Anti-progestin therapy targets hallmarks of breast cancer risk through epithelial-stromal remodelling
10:45 – 11:15 Break
The tumour microenvironment and metastasis
11:15 – 11:45 Clare Isacke – The role of CAFs in driving metastasis
11:45 – 12:15 Raza Ali – Understanding the evolving face of immune response
12:15 – 12:30 Ute Jungwirth - How chemotherapy alters the tumour microenvironment in breast cancer
12:30 – 12:45 Daniele Di Biagio - Adiponectin may regulate integrin avb6-dependent breast cancer growth and metastasis
12:45 – 13:15 Oral and poster prizes (1st and 2nd)
Packed lunch to take away
If you have any special dietary requirements - please let us know.
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BACR is a registered charity in England and Wales (289297)
Registered address:
c/o Leeds Institute of Medical Research at St James’s, Cancer Genetics Building,
St James's University Hospital, Beckett Street, Leeds LS9 7TF
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