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Despite substantial improvements in recent decades, the prognosis for those cancer patients who suffer from metastatic disease and depend on systemic drug therapy remains poor. Both intrinsic resistance and the formation of acquired drug resistance substantially affects the efficacy of cancer drugs. The advancement of precision medicine approaches holds promise for both the effective guidance of therapies to patients that will respond and the ability to monitor this tumour response. This will require the successful interpretation of ‘omics’ data and a close collaboration between pre-clinical researchers, clinicians, and computational biologists in both academia and industry to develop these strategies. This conference will bring together and showcase cancer researchers from these areas, who will present and discuss the latest advances in understanding the mechanisms of drug resistance in cancer, the identification of biomarkers of drug sensitivity/resistance and how they can be linked to precision medicine approaches.
• Molecular mechanisms of resistance and treatment response
• Genomics, systems biology and tumour evolution
• Models of tumour resistance
• Immuno-oncology and therapy
• Biomarkers of treatment and response
Gad Getz - Broad Institute / MIT
Julian Downward -The Francis Crick Institute, London
Xin Lu - Ludwig Cancer Research / Oxford
Hilde Loge Nilsen - University of Oslo
Mariam Jamal-Hanjani - University College London
Rachel Grimley – Cancer Research Horizons
Isle Rooman - Vrije University Brussels
Roland Rad – Technical University of Munich
Colm Ryan – University College Dublin
Martin Michaelis – University of Kent
Angeliki Malliri – CRUK Manchester Institute
Johann de Bono – Institute of Cancer Research
James Brenton – CRUK Cambridge Institute
Tim Fenton
Michelle Garrett
Martin Michaelis
Mark Wass
Poster presentation
Multiple short talks from submitted Abstracts
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BACR is a registered charity in England and Wales (289297)
Registered address:
c/o Leeds Institute of Medical Research at St James’s, Cancer Genetics Building,
St James's University Hospital, Beckett Street, Leeds LS9 7TF
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